Clostridium difficile is a harmful bacterium that can cause severe, recurrent and sometimes fatal infections in the gut. Although the bacteria are commonly found throughout our environment, C. diff infections primarily occur in patients who are taking, or who have recently finished taking, antibiotics.
Until recently, this was a mystery. New research, however, has found the cause: the antibiotics kill off native, healthy gut bacteria which would normally compete with C. diff for food.
The result is that the gut becomes an all-you-can-eat buffet for the invading bacteria, which gorge themselves on an amino acid called proline and then multiply like crazy.
In the image above, the bacteria are shown in the process of sporulation, which is the creation of spores that can lie dormant for long periods of time when circumstances are unfavourable before bursting to life when the time is right.
Read science facts, not fiction...
There’s never been a more important time to explain the facts, cherish evidence-based knowledge and to showcase the latest scientific, technological and engineering breakthroughs. Cosmos is published by The Royal Institution of Australia, a charity dedicated to connecting people with the world of science. Financial contributions, however big or small, help us provide access to trusted science information at a time when the world needs it most. Please support us by making a donation or purchasing a subscription today.