Cancer cells turn to cannibalism
It helps them survive chemotherapy, study suggests.
Some cancer cells survive chemotherapy by eating their neighbouring tumour cells, according to new research.
Writing in the Journal of Cell Biology, a team from Tulane University, US, suggests this act provides the cells with the energy they need to stay alive and initiate tumour relapse after the course of treatment is completed.
Crystal Tonnessen-Murray and colleagues report observing this surprising behaviour not only in cancer cells grown in the lab, but also in tumours growing in mice.
Lung and bone cancer cells are capable of the same trick, they discovered, noting that finding a way to inhibit this process may provide new therapeutic opportunities.